Services
Phage therapy
Phage therapy is a cutting-edge treatment approach that harnesses the natural ability of bacteriophages, viruses that infect and destroy bacteria, to combat bacterial infections. This therapeutic strategy has gained attention, especially in regions grappling with antibiotic resistance. In phage therapy, specific bacteriophages are carefully selected or engineered to target the precise strain of bacteria causing the infection. PhageLytix has made significant strides in combating bacterial infections by pioneering the development of a diverse array of phage preparations and potent cocktails. These innovative formulations hold tremendous promise in addressing a wide spectrum of ailments, including urinary tract infections, gastroenteritis, skin infections, prostatitis, and pneumonia.
In the realm of urinary tract infections, gastroenteritis, and skin infections, PhageLytix’s formulations offer a novel therapeutic avenue, potentially sidestepping the challenges posed by antibiotic resistance and providing patients with effective treatment options. Moreover, their efforts extend to addressing complex conditions like prostatitis and pneumonia, where conventional treatments may fall short.
Through ongoing research, clinical trials, and collaboration with healthcare providers, PhageLytix continues to advance the frontier of phage therapy, ushering in a new era of precision medicine tailored to combat bacterial infections across diverse clinical scenarios.
Genome analysis
At PhageLytix, we specialize in comprehensive phage genome analysis services tailored to meet your research and development needs. Our advanced capabilities include not only phage annotation and variant calling but also a range of additional analyses to provide deep insights into phage biology and function.
Our team of experts utilizes state-of-the-art bioinformatics tools and methodologies to accurately annotate phage genomes, identifying key features such as genes, promoters, and regulatory elements. We go beyond basic annotation to uncover genetic variations within phage populations, enabling precise variant calling and characterization.
In addition to standard analyses, we offer specialized services such as comparative genomics, which allows for the identification of evolutionary relationships between phages and the discovery of conserved or unique genetic elements. Our comprehensive approach facilitates the exploration of phage diversity, evolution, and potential applications in various fields, including biotechnology, agriculture, and medicine.
Partner with PhageLytix to unlock the full potential of phage genomics and gain a deeper understanding of these remarkable biological entities. Together, we can advance scientific knowledge, develop innovative solutions, and make a positive impact on diverse industries and fields.
Phage Hunting
Our company specializes in on-demand phage-hunting services worldwide, targeting any bacterial strain. We provide rapid isolation, purification, and testing of phages within days. Our streamlined process ensures swift access to potential phage candidates for therapeutic applications. With cutting-edge technology and expertise, we deliver reliable and potent phage products. We adhere to stringent quality standards to guarantee efficacy and safety. Harnessing the power of phages, we combat antibiotic-resistant pathogens and address unmet medical needs. Our services cater to healthcare providers, researchers, and biopharmaceutical companies. Partner with us to unlock the therapeutic potential of phages and revolutionize medicine. Explore the vast possibilities of personalized, precision phage therapy with our efficient and reliable solutions. Join us in shaping the future of bacterial infection treatment.
Endotoxin testing
Our company, PhageLytix, provides endotoxin testing in phage preparations. Endotoxin testing is crucial before progressing to clinical trials or administering treatment to patients on compassionate grounds. Ensuring the appropriate levels of endotoxin is essential for safety and efficacy. We measure endotoxin levels by qualitative gel clot LAL assay (Charles River). The gel clot LAL assay involves mixing the LAL reagent with the test sample in a tube, which is then incubated. If endotoxin is present in the sample, the clotting response by the LAL reagent is initiated.
Phage purification
PhageLytix offers advanced phage purification facilities adhering to Good Laboratory Practice (GLP) guidelines. The production of phages for therapeutic use demands rapid, efficient, and scalable purification methods. Phage lysates contain various impurities, including endotoxins from gram-negative bacteria and protein toxins produced by pathogenic bacterial species, which pose risks to human health. The maximum permissible endotoxin concentration for parenterally administered medications is 5 EU/kg/hr. The objective of this service is to assess the viability of various purification techniques in detecting and eliminating endotoxins during the production of phage preparations for clinical applications.